[Morphofunctional state of neutrophil granulocytes in Chernobyl nuclear plant accident clean-up workers with persistent leukopenia]. / Morfofunktsional'noe sostoianie neitrofil'nykh granulotsitov u uchastnikov likvidatsii posledstvii avarii na ChAES so stoikoi leikopeniei.

The obtained results of the analysis of the peripherical blood granulocytes morphofunctional condition in those persons who took part in the elimination of aftermaths of the Chernobyl accident, presenting with persistent leucopenia, suggest to us the presence of significant changes in morphological, cytochemical, and functional indices in the remote period.

[Functional status of the endocrine system in patients with hypertrophic cardiomyopathy]. / Funktsiona'lnoe sostoianie éndokrinnoi sistemy u bo'lnykh s gipertroficheskoi kardiomiopatiei.

The study was undertaken to examine 27 patients aged 20 to 50 years who had hypertrophic cardiomyopathy (HC). Group 1 consisted of 12 patients with asymmetric cardiomyopathy. Group 2 comprised 15 with symmetric cardiomyopathy. Blood samples were taken from the cubital vein before and 30 and 60 minutes after administration of 0.2 mg thyroid-releasing hormone (TRH). Blood hormone concentrations were measured by radioimmunoassay. TRH test was found to provide an essential information on the function of the hypothalamo-hypophyseal-thyroid and hypothalamohypophyseal-adrenal systems in HC patients. The HC patients showed lower function of the hypothalamo-hypophyseal-adrenal system. There was a decrease in serum testosterone during all the periods of examination. At the same time the patients from Groups 1 and 2 had substantial features of the function of various links of the immune system, which may suggest a variance in the pathogenesis of the two types of the disease.

[Disorders of immunity in alcoholic patients with myocardial infarction]. / Narusheniia immuniteta u bol'nykh infarktom miokarda, zloupotrebliavshikh alkogolem.

Cell-mediated immunity was assessed in myocardial infarction patients with and without a history of alcohol abuse. Patients with chronic alcoholic intoxication (CAI) showed a deficiency of T cells, abnormal proportions of immunocompetent cells and impaired tissue antigen recognition resulting in autoimmune disorders. Practicability of immunocorrection in myocardial infarction patients with CAI is discussed.

[Lysozyme content in biological substrates and immunological indices of the blood in pneumonia patients]. / Soderzhanie lizotsima v biologicheskikh substratakh i immunologicheskie pokazateli krovi bol'nykh pnevmoniei.

An increase of lysozyme content in biological fluids observed during treatment of pulmonary diseases was shown to be followed by positive immunological and clinical effects. The parameters of immunological properties of lysozyme determined on the patient blood cells in vitro (before treatment) may be used for prediction of the drug efficacy during treatment.